Evolution of the mitochondrial genetic code. IV. AAA as an asparagine codon in some animal mitochondria

J Mol Evol. 1990 Apr;30(4):329-32. doi: 10.1007/BF02101887.

Abstract

Differences in assignments from those in the universal genetic code occur in codes of mitochondria. In this report, the published sequences of the mitochondrial genes for COI and ND1 in a platyhelminth (Fasciola hepatica) are examined and it is concluded that AAA may be a codon for asparagine instead of lysine, whereas AAG is the sole codon for lysine in this species.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Asparagine / genetics*
  • Bacteria / genetics
  • Base Sequence
  • Biological Evolution*
  • Codon / genetics*
  • Echinodermata / genetics
  • Fasciola hepatica / genetics*
  • Genetic Code
  • Humans
  • Insecta / genetics
  • Mammals / genetics
  • Mitochondria*
  • Molecular Sequence Data
  • RNA, Messenger / genetics*
  • RNA, Transfer, Lys / genetics

Substances

  • Codon
  • RNA, Messenger
  • RNA, Transfer, Lys
  • Asparagine