Complete genome sequence of Brachyspira murdochii type strain (56-150)

Stand Genomic Sci. 2010 Jun 15;2(3):260-9. doi: 10.4056/sigs.831993.

Abstract

Brachyspira murdochii Stanton et al. 1992 is a non-pathogenic, host-associated spirochete of the family Brachyspiraceae. Initially isolated from the intestinal content of a healthy swine, the 'group B spirochaetes' were first described as Serpulina murdochii. Members of the family Brachyspiraceae are of great phylogenetic interest because of the extremely isolated location of this family within the phylum 'Spirochaetes'. Here we describe the features of this organism, together with the complete genome sequence and annotation. This is the first completed genome sequence of a type strain of a member of the family Brachyspiraceae and only the second genome sequence from a member of the genus Brachyspira. The 3,241,804 bp long genome with its 2,893 protein-coding and 40 RNA genes is a part of the Genomic Encyclopedia of Bacteria and Archaea project.

Keywords: Brachyspiraceae; GEBA; Gram-negative; Spirochaetes; anaerobic; host-associated; motile; non-pathogenic.