Paraganglioma: a diagnostic dilemma

J Pak Med Assoc. 2010 Sep;60(9):789-91.

Abstract

We report a case of intra abdominal paraganglioma in a 46-year-old male, that measured 12.5 x 10 x 10 cm and weighed 340 grams. A CT scan was done for the evaluation of an abdominal mass. The tumour was surgically removed and followed by an uneventful post operative recovery. On follow up at one year patient had no active complaints. Histologically paraganglioma was composed of tumour cells that had abundant, granular to clear eosinophilic cytoplasm and mildly pleomorphic, vesicular rounded nuclei. Occasional mitoses was seen. No atypia was noticed. Immunohistochemistry confirmed the presence of chromogranin, synaptophysin and vimentin markers. These are diagnostic for paraganglioma.

Publication types

  • Case Reports

MeSH terms

  • Abdominal Neoplasms / diagnosis*
  • Abdominal Neoplasms / surgery
  • Follow-Up Studies
  • Humans
  • Immunohistochemistry
  • Male
  • Middle Aged
  • Paraganglioma, Extra-Adrenal / diagnosis*
  • Paraganglioma, Extra-Adrenal / surgery
  • Tomography, X-Ray Computed
  • Treatment Outcome