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The first identification of lysine malonylation substrates and its regulatory enzyme.
Peng C, Lu Z, Xie Z, Cheng Z, Chen Y, Tan M, Luo H, Zhang Y, He W, Yang K, Zwaans BM, Tishkoff D, Ho L, Lombard D, He TC, Dai J, Verdin E, Ye Y, Zhao Y. Peng C, et al. Mol Cell Proteomics. 2011 Dec;10(12):M111.012658. doi: 10.1074/mcp.M111.012658. Epub 2011 Sep 9. Mol Cell Proteomics. 2011. PMID: 21908771 Free PMC article.
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase.
Du J, Zhou Y, Su X, Yu JJ, Khan S, Jiang H, Kim J, Woo J, Kim JH, Choi BH, He B, Chen W, Zhang S, Cerione RA, Auwerx J, Hao Q, Lin H. Du J, et al. Science. 2011 Nov 11;334(6057):806-9. doi: 10.1126/science.1207861. Science. 2011. PMID: 22076378 Free PMC article.