TOP3A, a new partner gene fused to MLL in an adult patient with de novo acute myeloid leukaemia

Br J Haematol. 2012 Apr;157(1):128-31. doi: 10.1111/j.1365-2141.2011.08908.x. Epub 2011 Nov 3.

Authors

Charles Herbaux, Stephanie Poulain, Claus Meyer, Rolf Marschalek, Aline Renneville, Jose Fernandes, Olivier Theisen, Sabine Tricot, Marc Simon, Patrick Duthilleul, Agnes Daudignon

PMID: 22050635
DOI: 10.1111/j.1365-2141.2011.08908.x

No abstract available

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Chromosomes, Human, Pair 11 / genetics*
Chromosomes, Human, Pair 11 / metabolism
Chromosomes, Human, Pair 17 / genetics*
Chromosomes, Human, Pair 17 / metabolism
DNA Topoisomerases, Type I / genetics*
DNA Topoisomerases, Type I / metabolism
Histone-Lysine N-Methyltransferase
Humans
Leukemia, Myeloid, Acute / blood
Leukemia, Myeloid, Acute / genetics*
Leukemia, Myeloid, Acute / pathology
Male
Middle Aged
Myeloid-Lymphoid Leukemia Protein / genetics*
Myeloid-Lymphoid Leukemia Protein / metabolism
Oncogene Proteins, Fusion / genetics*
Oncogene Proteins, Fusion / metabolism
Translocation, Genetic*

Substances

KMT2A protein, human
Oncogene Proteins, Fusion
Myeloid-Lymphoid Leukemia Protein
Histone-Lysine N-Methyltransferase
DNA Topoisomerases, Type I