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Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH.
EMBO Rep. 2011 Dec 1;12(12):1300-5. doi: 10.1038/embor.2011.205.
EMBO Rep. 2011.
PMID: 22081141
Free PMC article.
Annexin A2 is a natural extrahepatic inhibitor of the PCSK9-induced LDL receptor degradation.
Seidah NG, Poirier S, Denis M, Parker R, Miao B, Mapelli C, Prat A, Wassef H, Davignon J, Hajjar KA, Mayer G.
Seidah NG, et al.
PLoS One. 2012;7(7):e41865. doi: 10.1371/journal.pone.0041865. Epub 2012 Jul 27.
PLoS One. 2012.
PMID: 22848640
Free PMC article.
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