Granulomatous angiitis of the CNS revealing a Hodgkin lymphoma

Neurology. 2013 Jan 15;80(3):323-4. doi: 10.1212/WNL.0b013e31827deb26. Epub 2012 Dec 26.

Abstract

Apart from the iatrogenic effects of treatment, neurologic complications of Hodgkin lymphoma (HL) can be divided into direct (meningeal or intracranial/spinal localization) and indirect (paraneoplastic/immune complications).(1) Here, we present a patient with granulomatous angiitis of the CNS (GANS) associated with HL that dramatically improved after the treatment of the angiitis by cyclophosphamide, methylprednisolone, and specific chemotherapy.

Publication types

  • Case Reports

MeSH terms

  • Anti-Inflammatory Agents / therapeutic use
  • Antineoplastic Agents, Alkylating / therapeutic use
  • Cyclophosphamide / therapeutic use
  • Hodgkin Disease / complications*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Methylprednisolone / therapeutic use
  • Middle Aged
  • Respiration, Artificial
  • Tomography, X-Ray Computed
  • Vasculitis, Central Nervous System / drug therapy
  • Vasculitis, Central Nervous System / etiology*

Substances

  • Anti-Inflammatory Agents
  • Antineoplastic Agents, Alkylating
  • Cyclophosphamide
  • Methylprednisolone

Supplementary concepts

  • Granulomatous Angiitis of the Central Nervous System