Abstract
Paragangliomas are rare benign neuroendocrine tumors, and 80% of all paragangliomas are either carotid body tumors or glomus jugulare tumors. We present a case of recurrent unresectable carotid body paraganglioma with nodal and T7 vertebral metastases in a 30-year-old man 6 years postsurgery detected with Ga DOTANOC PET/CT and was administered with peptide receptor radionuclide therapy using Lu DOTATATE. After 5 cycles of Lu DOTATATE (total cumulative activity of 750 mCi [27 GBq]), significant response at the primary site on Ga DOTANOC PET/CT and complete disappearance of nodal and T7 vertebral metastases were noted.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Carotid Body Tumor / complications
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Carotid Body Tumor / diagnostic imaging*
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Carotid Body Tumor / drug therapy*
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Humans
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Male
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Neoplasm Recurrence, Local / complications
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Neoplasm Recurrence, Local / diagnostic imaging*
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Octreotide / analogs & derivatives*
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Octreotide / therapeutic use
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Organometallic Compounds / therapeutic use*
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Paraganglioma / complications
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Paraganglioma / diagnostic imaging*
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Radionuclide Imaging
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Spinal Neoplasms / complications
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Spinal Neoplasms / diagnostic imaging*
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Spinal Neoplasms / secondary*
Substances
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Organometallic Compounds
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lutetium Lu 177 dotatate
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Octreotide