Metastasizing "benign" pleomorphic salivary adenoma: a dramatic case-report and literature review

J Craniomaxillofac Surg. 2014 Dec;42(8):1562-5. doi: 10.1016/j.jcms.2014.01.014. Epub 2014 Jan 14.

Abstract

Pleomorphic salivary adenomas are the most common benign neoplasms affecting the salivary glands. Very occasionally however, metastatic lesions are identified in patients with a history of PSA, which, on detailed pathological evaluation, are found to exhibit all the histological hallmarks of the preceding benign lesions. Diagnosis of benign metastasizing pleomorphic adenoma of the salivary gland is extremely rare and still under debate. We present the first case-report in literature of multiple metachronous nasal cavity, scalp and encephalic metastases of a pleomorphic adenoma of the parotid gland in a young girl.

Keywords: Metastasizing pleomorphic salivary adenoma; Multiple pleomorphic adenomas; Parotid gland tumours.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenoma, Pleomorphic / pathology*
  • Brain Neoplasms / pathology
  • Child
  • Female
  • Follow-Up Studies
  • Head and Neck Neoplasms / pathology
  • Humans
  • Nasal Cavity / pathology
  • Nasal Obstruction / diagnosis
  • Neoplasms, Second Primary / pathology*
  • Nose Neoplasms / pathology
  • Parotid Neoplasms / pathology*
  • Scalp / pathology
  • Skin Neoplasms / pathology