Musculoskeletal manifestations of endocrine disorders

Clin Imaging. 2014 Jul-Aug;38(4):384-396. doi: 10.1016/j.clinimag.2014.02.014. Epub 2014 Mar 6.

Abstract

Endocrine disorders can lead to disturbances in numerous systems within the body, including the musculoskeletal system. Radiological evaluation of these conditions can demonstrate typical appearances of the bones and soft tissues. Knowledge of these patterns can allow the radiologist to suggest a diagnosis that may not be clinically apparent. This review will highlight the typical musculoskeletal findings of acromegaly, hypercortisolism, hyperthyroidism, hypothyroidism, hyperparathyroidism, pseudo- and pseudopseudohypoparathyroidism, and diabetes mellitus. The radiological manifestations of each of these endocrine disorders, along with a brief discussion of the pathophysiology and clinical implications, will be discussed.

Keywords: Acromegaly; Diabetes; Hypercortisolism; Parathyroid; Thyroid.

Publication types

  • Review

MeSH terms

  • Acromegaly / diagnostic imaging
  • Cushing Syndrome / diagnostic imaging
  • Diabetes Mellitus / diagnostic imaging
  • Endocrine System Diseases / diagnostic imaging*
  • Female
  • Humans
  • Hyperparathyroidism / diagnostic imaging
  • Hyperthyroidism / diagnostic imaging
  • Hypothyroidism / diagnostic imaging
  • Magnetic Resonance Imaging*
  • Male
  • Musculoskeletal Diseases / diagnostic imaging*
  • Pseudohypoparathyroidism / diagnostic imaging
  • Pseudopseudohypoparathyroidism / diagnostic imaging
  • Tomography, X-Ray Computed*