Intracranial infantile hemangiopericytoma

J Neurosurg Pediatr. 2014 Aug;14(2):149-54. doi: 10.3171/2014.4.PEDS13463. Epub 2014 Jun 6.

Abstract

Intracranial infantile hemangiopericytomas (HPCs) are exceedingly rare lesions. Only 11 cases have been previously reported in the literature. As such, little is known about the etiology, long-term prognosis, and optimal treatment paradigm. Clinically, they are consistently less aggressive than those in adults. The authors present the case of a 2-month-old boy with an intracranial HPC, review the available literature, discuss the evolving concepts of what defines an HPC, and offer a potential explanation to how HPC histology might relate to the clinical behavior of these lesions.

Keywords: HPC = hemangiopericytoma; SFT = solitary fibrous tumor; hemangiopericytoma; infantile; intracranial; oncology; pediatric.

Publication types

  • Case Reports

MeSH terms

  • Brain / pathology*
  • Brain Neoplasms / diagnosis*
  • Brain Neoplasms / pathology
  • Brain Neoplasms / therapy*
  • Hemangiopericytoma / diagnosis*
  • Hemangiopericytoma / pathology
  • Hemangiopericytoma / therapy*
  • Humans
  • Infant
  • Magnetic Resonance Imaging
  • Male
  • Prognosis