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2014 | 1 |
2017 | 1 |
2018 | 1 |
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TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis.
Sci Transl Med. 2014 Jul 2;6(243):243ra86. doi: 10.1126/scitranslmed.3009093.
Sci Transl Med. 2014.
PMID: 24990881
TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant.
Thornton P, Sevalle J, Deery MJ, Fraser G, Zhou Y, Ståhl S, Franssen EH, Dodd RB, Qamar S, Gomez Perez-Nievas B, Nicol LS, Eketjäll S, Revell J, Jones C, Billinton A, St George-Hyslop PH, Chessell I, Crowther DC.
Thornton P, et al.
EMBO Mol Med. 2017 Oct;9(10):1366-1378. doi: 10.15252/emmm.201707673.
EMBO Mol Med. 2017.
PMID: 28855301
Free PMC article.
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The metalloprotease ADAM10 (a disintegrin and metalloprotease 10) undergoes rapid, postlysis autocatalytic degradation.
Brummer T, Pigoni M, Rossello A, Wang H, Noy PJ, Tomlinson MG, Blobel CP, Lichtenthaler SF.
Brummer T, et al.
FASEB J. 2018 Jul;32(7):3560-3573. doi: 10.1096/fj.201700823RR. Epub 2018 Feb 7.
FASEB J. 2018.
PMID: 29430990
Free PMC article.
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