Neonatal polycystic kidney disease

Priya Verghese; Yosuke Miyashita

doi:10.1016/j.clp.2014.05.005

Neonatal polycystic kidney disease

Clin Perinatol. 2014 Sep;41(3):543-60. doi: 10.1016/j.clp.2014.05.005. Epub 2014 Jul 19.

Authors

Priya Verghese¹, Yosuke Miyashita²

Affiliations

¹ Division of Pediatric Nephrology, Department of Pediatrics, Amplatz Children's Hospital, University of Minnesota, 2450 Riverside Avenue, MB 682, Minneapolis, MN 55454, USA. Electronic address: pverghes@umn.edu.
² Division of Pediatric Nephrology, Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, 4401 Penn Avenue, Pittsburgh, PA 15224, USA.

PMID: 25155726
DOI: 10.1016/j.clp.2014.05.005

Abstract

This article provides an up-to-date comprehensive review and summary on neonatal polycystic kidney disease (PKD) with emphasis on the differential diagnosis, clinical manifestations, diagnostic techniques, and potential therapeutic approaches for the major causes of neonatal PKD, namely hereditary disease, including autosomal recessive and autosomal dominant PKD and nonhereditary PKD, with particular emphasis on multicystic dysplastic kidney. A brief overview of obstructive cystic dysplasia and simple and complex cysts is also included.

Keywords: ADPKD; ARPKD; Multicystic dysplastic kidney; Polycystic kidney; Renal cyst.

Publication types

Review

MeSH terms

Diagnosis, Differential
Disease Management*
Global Health
Humans
Incidence
Infant, Newborn
Polycystic Kidney Diseases* / diagnosis
Polycystic Kidney Diseases* / epidemiology
Polycystic Kidney Diseases* / therapy