Hobnail Hemangioma (Superficial Hemosiderotic Lymphovascular Malformation) in Children: A Series of 6 Pediatric Cases and Review of the Literature

J Cutan Med Surg. 2016 May;20(3):216-20. doi: 10.1177/1203475415612421. Epub 2015 Oct 16.

Abstract

Background: Hobnail hemangioma is a small benign vascular malformation of the superficial and mid-dermis with variable clinical presentation.

Objectives: To review the clinical characteristics of hobnail hemangioma in pediatric patients.

Methods: A retrospective chart review performed of all histopathologically confirmed cases of hobnail hemangioma from May 2000 to December 2014. Data on demographics, clinical characteristics, and results of immunohistochemical staining were collected.

Results: Four male and 2 female patients identified. Congenital lesions were reported in 3 cases. The most common anatomic location was the extremities. Treatment options included observation and surgical excision.

Conclusions: Hobnail hemangioma is an uncommon benign vascular malformation. Due to its benign nature, treatment is not required. If treatment is indicated, complete surgical excision appears to be the most effective option.

Keywords: hobnail hemangioma; superficial hemosiderotic lymphovascular malformation; targetoid hemosiderotic hemangioma.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Antibodies, Monoclonal, Murine-Derived / analysis
  • Child
  • Female
  • Glucose Transporter Type 1 / analysis
  • Hemangioma / chemistry*
  • Hemangioma / diagnosis*
  • Hemangioma / pathology
  • Humans
  • Male
  • Platelet Endothelial Cell Adhesion Molecule-1 / analysis
  • Skin Neoplasms / chemistry*
  • Skin Neoplasms / diagnosis*
  • Skin Neoplasms / pathology
  • WT1 Proteins / analysis

Substances

  • Antibodies, Monoclonal, Murine-Derived
  • Glucose Transporter Type 1
  • Platelet Endothelial Cell Adhesion Molecule-1
  • WT1 Proteins
  • WT1 protein, human
  • monoclonal antibody D2-40