Ranking occupational contexts associated with risk of non-Hodgkin lymphoma

Background: Risk factors associated with non-Hodgkin lymphoma (NHL) remain unknown, but certain occupational contexts (OCs) have been implicated. The objective of this study was to inventory, from the accumulated knowledge, associations between OCs and NHL risk.

Methods: Literature was used to identify the NHL-associated OCs. For each context, items were ranked both by scientific interest and the association strength.

Results: Three ranked lists of OCs related to NHL were constructed. We found that NHL was associated with 31 occupational activities, 91 occupational exposures, and 35 occupational activity-exposure combinations. Among them, 5 activities, 2 exposures, and 3 combinations, involving agricultural or industrial sector and solvents or pesticides, were highlighted with the highest publications number and the strongest association with NHL risk.

Conclusion: These results could be useful in both providing a ranked inventory of OCs associated with NHL risk and highlighting "hot" occupational activities and exposures. Am. J. Ind. Med. 59:561-574, 2016. © 2016 Wiley Periodicals, Inc.