Initial Diagnosis and Management of Coma

Emerg Med Clin North Am. 2016 Nov;34(4):777-793. doi: 10.1016/j.emc.2016.06.017. Epub 2016 Sep 3.

Abstract

Coma represents a true medical emergency. Drug intoxications are a leading cause of coma; however, other metabolic disturbances and traumatic brain injury are also common causes. The general emergency department approach begins with stabilization of airway, breathing, and circulation, followed by a thorough physical examination to generate a limited differential diagnosis that is then refined by focused testing. Definitive treatment is ultimately disease-specific. This article presents an overview of the pathophysiology, causes, examination, and treatment of coma.

Keywords: Coma; Coma mimics; Pathophysiology.

Publication types

  • Review

MeSH terms

  • Coma / diagnosis*
  • Coma / etiology
  • Coma / therapy
  • Diagnosis, Differential
  • Emergency Service, Hospital*
  • Humans
  • Physical Examination