Photorefractive Keratectomy With Mitomycin C in Meesmann's Epithelial Corneal Dystrophy

J Refract Surg. 2017 Jan 1;33(1):53-55. doi: 10.3928/1081597X-20161027-03.

Abstract

Purpose: To describe a case of Meesmann's epithelial corneal dystrophy that underwent photorefractive keratectomy (PRK) with mitomycin C.

Methods: Case report.

Results: A 36-year-old woman was evaluated for refractive surgery. She had a history of recurrent epithelial erosions and moderate visual loss over the past 10 years. Biomicroscopy revealed bilateral micro-cystic epithelial lesions and a diagnosis of Meesmann's epithelial corneal dystrophy was proposed. Corneal optical coherence tomography showed epithelial thickening with apparent intraepithelial cysts in the superficial layers. The patient's daughter's examination showed the same biomicroscopy pattern. PRK was performed. Epithelial healing was uneventful and only tiny microcysts could be observed after 3 months. However, complete recurrence of the intraepithelial cysts were observed after 1 year with visual acuity dropping due to residual refractive error.

Conclusions: This case suggests that residual refractive error and recurrence of the cystic lesions and punctate erosions should be anticipated after PRK in patients with Meesmann's epithelial corneal dystrophy. [J Refract Surg. 2017;33(1):53-55.].

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Alkylating Agents / administration & dosage*
  • Combined Modality Therapy
  • Corneal Dystrophy, Juvenile Epithelial of Meesmann / drug therapy
  • Corneal Dystrophy, Juvenile Epithelial of Meesmann / physiopathology
  • Corneal Dystrophy, Juvenile Epithelial of Meesmann / surgery
  • Corneal Dystrophy, Juvenile Epithelial of Meesmann / therapy*
  • Corneal Pachymetry
  • Corneal Topography
  • Epithelium, Corneal / pathology
  • Female
  • Humans
  • Lasers, Excimer / therapeutic use*
  • Mitomycin / administration & dosage*
  • Photorefractive Keratectomy / methods*
  • Visual Acuity / physiology
  • Wound Healing / physiology

Substances

  • Alkylating Agents
  • Mitomycin