Infections of the Nervous System

Am J Med. 2018 Jan;131(1):25-32. doi: 10.1016/j.amjmed.2017.08.020. Epub 2017 Sep 7.

Abstract

Microorganisms can affect the entire neuraxis, producing a variety of neurologic complications that frequently entail prolonged hospitalizations and complicated treatment regimens. The spread of pathogens to new regions and the reemergence of opportunistic organisms in immunocompromised patients pose increasing challenges to health care professionals. Because rapid diagnosis and treatment may prevent long-term neurologic sequelae, providers should approach these diseases with a structured, neuroanatomic framework, incorporating a thorough history, examination, laboratory analysis, and neuroimaging in their clinical reasoning and decision-making.

Keywords: Encephalitis; Meningitis; Mononeuritis multiplex; Pyogenic abscess; Transverse myelitis.

Publication types

  • Review

MeSH terms

  • Central Nervous System Infections / diagnosis*
  • Central Nervous System Infections / pathology*
  • Humans
  • Immunocompromised Host
  • Infectious Disease Transmission, Patient-to-Professional
  • Opportunistic Infections
  • Peripheral Nervous System Diseases / microbiology*
  • Stroke / etiology
  • Stroke / microbiology
  • Stroke / pathology