Clinical applications of multiparametric CMR in left ventricular hypertrophy

Int J Cardiovasc Imaging. 2018 Apr;34(4):577-585. doi: 10.1007/s10554-018-1320-6. Epub 2018 Mar 3.

Abstract

There are a number of diseases which can increase left ventricular myocardial wall thickness through a number of different mechanisms. Multi-parametric mapping techniques are a new addition to the cardiovascular magnetic resonance (CMR) armoury with a number of potential clinical roles. In this review article, we will explore the role of imaging in left ventricular hypertrophy, and particularly developments in CMR. We focus on ability of CMR to characterize myocardial tissue using multiparametric mapping (native T1, T2 and extracellular volume mapping), to bridge from the microscopic histological domain and into the clinical domain of non-invasive imaging.

Keywords: Extracellular volume mapping; Late gadolinium enhancement; Left ventricular hypertrophy; Multi-parametric mapping; Native T1; T2 mapping.

Publication types

  • Review

MeSH terms

  • Cardiomyopathies / diagnostic imaging*
  • Cardiomyopathies / pathology
  • Cardiomyopathies / physiopathology
  • Contrast Media / administration & dosage
  • Fibrosis
  • Heart Ventricles / diagnostic imaging*
  • Heart Ventricles / pathology
  • Heart Ventricles / physiopathology
  • Humans
  • Hypertrophy, Left Ventricular / diagnostic imaging*
  • Hypertrophy, Left Ventricular / pathology
  • Hypertrophy, Left Ventricular / physiopathology
  • Image Interpretation, Computer-Assisted
  • Magnetic Resonance Imaging*
  • Predictive Value of Tests
  • Prognosis
  • Ventricular Function, Left
  • Ventricular Remodeling

Substances

  • Contrast Media