Central scotoma in tobacco-alcohol toxic optic neuropathy measured with semi-automated kinetic perimetry

Cutan Ocul Toxicol. 2018 Dec;37(4):319-323. doi: 10.1080/15569527.2018.1459666. Epub 2018 Apr 24.

Abstract

Purpose: To measure the area of central scotoma obtained with semi-automated kinetic perimetry (SKP) in patients suffering from tobacco-alcohol toxic neuropathy (TATN).

Methods: Twelve eyes of six patients with TATN were examined with SKP. Area of central scotoma was measured in square degrees (deg2). Additionally, static automated perimetry (SAP) within 60° was performed in each patient.

Results: Area of central scotoma was 41.8 deg2 for III4e isopter, 22.9 deg2 for I4e isopter and 16.1 deg2 for I2e isopter in TATN patients. SAP revealed central scotoma in all patients. There was 100% of accordance between two methods.

Conclusion: SKP is comparable with SAP in assessing central scotoma. SKP offers advantage of measuring central scotoma and assessing remaining peripheral visual field in TATN, even with low incidence and prevalence of this clinical entity.

Keywords: Kinetic perimetry; central scotoma; isopter; static perimetry; toxic neuropathy.

MeSH terms

  • Adult
  • Automation
  • Cohort Studies
  • Ethanol / adverse effects*
  • Female
  • Humans
  • Male
  • Nicotiana / adverse effects*
  • Optic Nerve Diseases / chemically induced
  • Optic Nerve Diseases / diagnostic imaging*
  • Prospective Studies
  • Reproducibility of Results
  • Scotoma / chemically induced
  • Scotoma / diagnostic imaging*
  • Vision Tests
  • Visual Field Tests / methods*

Substances

  • Ethanol