Endoscopic-ultrasound-guided coil and cyanoacrylate embolization for gastric varices and the roles of endoscopic Doppler and endosonographic varicealography in vascular targeting

Dig Endosc. 2019 May;31(3):283-290. doi: 10.1111/den.13305. Epub 2018 Dec 18.

Abstract

Objective: To report the results of endoscopic ultrasound-guided injection of coils with cyanoacrylate (CYA) using a less-expensive coil with an emphasis on the roles of Doppler and endosonographic varicealography (EV) in identifying the feeder vessel in gastric varix treatment.

Methods: An observational, descriptive study with prospectively collected data. Patients with gastric varices (GV) were included and were treated by endoscopic ultrasound-guided injection of CYA and a less-expensive coil. Technical success, complete and immediate variceal obliteration, rebleeding, complication and survival rates were evaluated.

Results: Thirty patients with GV with a mean age of 62 years (range: 44-76 years) were treated. Median number of coils used was 2 (range: 1-3), and median volume of CYA was 1.8 mL (1.2-2.4 mL). Technical success rate was 100%. EV technical success was observed in 26/30 patients. Complete variceal obliteration was observed in 96.6% of patients, and immediate disappearance of the varix was observed in 24 (80%) patients. The complication rate was 6.7%.

Conclusions: Endoscopic-ultrasound guidance for gastric varix treatment with the addition of EV and the use of a less-expensive coil is a safe and effective technique that results in the immediate disappearance of GV after targeting the feeding vessel.

Keywords: cyanoacrylate; endoscopic ultrasonography; gastric variceal bleeding; gastric varices; gastrointestinal hemorrhage.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Aged
  • Cyanoacrylates / administration & dosage*
  • Embolization, Therapeutic / methods*
  • Endosonography / methods*
  • Esophageal and Gastric Varices / diagnostic imaging*
  • Esophageal and Gastric Varices / therapy*
  • Female
  • Gastroscopy / methods*
  • Hemostasis, Endoscopic / methods*
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • Tissue Adhesives / administration & dosage*

Substances

  • Cyanoacrylates
  • Tissue Adhesives

Associated data

  • GENBANK/NCT03277937