Skin diseases of the breast and nipple: Benign and malignant tumors

J Am Acad Dermatol. 2019 Jun;80(6):1467-1481. doi: 10.1016/j.jaad.2018.08.066. Epub 2018 Nov 16.

Abstract

The evaluation and management of dermatologic diseases of the breast and nipple requires an understanding of the unique anatomy of the breast and nipple and an awareness of the significant emotional, cultural, and sexual considerations that may come into play when treating this anatomic area. The first article in this continuing medical education series reviews breast anatomy, congenital breast anomalies, and benign and malignant breast tumors. An emphasis is placed on inflammatory breast cancer and breast cancer with noninflammatory skin involvement and on cutaneous metastases to the breast and from breast cancer. Familiarity of the dermatologist with the cutaneous manifestations of breast cancer will facilitate the diagnosis of breast malignancy and assist with staging, prognostication, and evaluation for recurrence. This article also discusses genodermatoses that predispose to breast pathology and provides imaging recommendations for evaluating a palpable breast mass.

Keywords: Paget disease; breast; breast cancer; continuing medical education; genodermatoses; nipple.

Publication types

  • Review

MeSH terms

  • Breast / abnormalities
  • Breast / anatomy & histology
  • Breast Diseases* / classification
  • Breast Diseases* / diagnosis
  • Breast Diseases* / embryology
  • Breast Diseases* / pathology
  • Breast Neoplasms / classification
  • Breast Neoplasms / diagnosis
  • Breast Neoplasms / pathology
  • Breast Neoplasms / secondary
  • Disease Management
  • Female
  • Genetic Predisposition to Disease
  • Humans
  • Male
  • Nipples / abnormalities
  • Nipples / embryology
  • Nipples / pathology

Supplementary concepts

  • Polythelia, Familial