MRI in autosomal dominant polycystic kidney disease

Weiguo Zhang; Jon D Blumenfeld; Martin R Prince

doi:10.1002/jmri.26627

MRI in autosomal dominant polycystic kidney disease

J Magn Reson Imaging. 2019 Jul;50(1):41-51. doi: 10.1002/jmri.26627. Epub 2019 Jan 13.

Authors

Weiguo Zhang¹, Jon D Blumenfeld², Martin R Prince^{1

3}

Affiliations

¹ Department of Radiology, Weill Cornell Medicine, New York, New York, USA.
² Rogosin Institute, and Department of Medicine, Weill Cornell Medicine, New York, New York, USA.
³ Columbia College of Physicians and Surgeons, New York, New York, USA.

PMID: 30637853
DOI: 10.1002/jmri.26627

Abstract

Magnetic resonance imaging (MRI) is increasingly used in autosomal dominant polycystic kidney disease (ADPKD) for diagnosis, classification, assessment of disease progression and treatment response, and for identifying complications. Herein we review the role of MRI in the management of patients with ADPKD. We show how MRI-derived total kidney volume is a biomarker for assessing ADPKD severity and predicting decline in renal function. We also demonstrate the MR appearances of common complications. Level of Evidence: 3 Technical Efficacy Stage: 5 J. Magn. Reson. Imaging 2019;50:41-51.

Keywords: ADPKD; arachnoid cyst; infected cyst; pancreatic cyst; total kidney volume; venous compression.

Publication types

Review

MeSH terms

Biomarkers / analysis
Disease Progression
Humans
Magnetic Resonance Imaging / methods*
Polycystic Kidney, Autosomal Dominant / complications
Polycystic Kidney, Autosomal Dominant / diagnostic imaging*
Polycystic Kidney, Autosomal Dominant / pathology
Predictive Value of Tests

Substances

Biomarkers