Managing vesicoureteral reflux in children: making sense of all the data

F1000Res. 2019 Jan 8:8:F1000 Faculty Rev-29. doi: 10.12688/f1000research.16534.1. eCollection 2019.

Abstract

Current management of vesicoureteral reflux (VUR) in children is the result of a steady albeit controversial evolution of data and thinking related to the clinical impact of VUR and urinary tract infection (UTI) in children, the value of clinical screening, and the relative impact of testing and interventions for VUR. While controversy continues, there is consensus on the importance of bladder dysfunction on VUR outcomes, the likelihood of VUR resolution, and the fact that not all children with VUR require active treatment. Early efforts to define risk stratification hold the most promise to provide more patient-specific treatment of UTI and VUR in children.

Keywords: Pediatric Vesicoureteral Reflux; Urinary tract infection; antibiotic prophylaxis; renal scarring.

Publication types

  • Review

MeSH terms

  • Child
  • Female
  • Humans
  • Male
  • Recurrence
  • Risk Factors
  • Urinary Tract Infections*
  • Vesico-Ureteral Reflux* / therapy

Grants and funding

The author(s) declared that no grants were involved in supporting this work.