Management of Asymptomatic Wolff-Parkinson-White Pattern by Pediatric Electrophysiologists

J Pediatr. 2019 Oct:213:88-95.e1. doi: 10.1016/j.jpeds.2019.05.058. Epub 2019 Jun 22.

Abstract

Objective: To determine the present-day approach of pediatric cardiac electrophysiologists to asymptomatic Wolff-Parkinson-White (WPW) pattern and to contrast to both published consensus statements and a similar survey.

Study design: A questionnaire was sent to 266 Pediatric and Congenital Electrophysiology Society physician members in 25 countries; 21 questions from the 2003 survey were repeated, with new questions added regarding risk stratification and decision making.

Results: We received 113 responses from 13 countries, with responders having extensive electrophysiology experience (median 15 years [IQR 8.5-25 years]). Only 12 (11%) believed that intermittent pre-excitation and 37 (33%) that sudden loss of pre-excitation on exercise test were sufficient evidence of accessory pathway safety to avoid an invasive electrophysiology study. Optimal weight for electrophysiology study was 20 kg (IQR 18-22.5 kg), and 61% and 58% would then ablate all right-sided or left-sided accessory pathways, respectively, regardless of electrophysiological properties, whereas only 23% would ablate all septal accessory pathways (P < .001). Compared with 2003, respondents were more likely to consider inducible arrhythmia (77% vs 26%, P < .001) as sufficient indication alone for ablation.

Conclusions: In the context of recent literature regarding the reliability of risk-stratification tools, most operators are now performing electrophysiology study for asymptomatic Wolff-Parkinson-White regardless of noninvasive findings. Many will then proceed to default ablation of all accessory pathways distant from critical conduction structures.

Keywords: Wolff-Parkinson-White; ablation; accessory pathway; electrophysiological study; pediatric; risk stratification; sudden cardiac death.

MeSH terms

  • Attitude of Health Personnel*
  • Catheter Ablation
  • Child
  • Electrocardiography
  • Female
  • Humans
  • Male
  • Pediatrics*
  • Reproducibility of Results
  • Surveys and Questionnaires
  • Wolff-Parkinson-White Syndrome / complications
  • Wolff-Parkinson-White Syndrome / diagnosis*
  • Wolff-Parkinson-White Syndrome / therapy*