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Epigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational program.
Acta Neuropathol. 2019 Dec;138(6):1053-1074. doi: 10.1007/s00401-019-02062-4. Epub 2019 Aug 19.
Acta Neuropathol. 2019.
PMID: 31428936
Free PMC article.
Loss of the ribosomal RNA methyltransferase NSUN5 impairs global protein synthesis and normal growth.
Heissenberger C, Liendl L, Nagelreiter F, Gonskikh Y, Yang G, Stelzer EM, Krammer TL, Micutkova L, Vogt S, Kreil DP, Sekot G, Siena E, Poser I, Harreither E, Linder A, Ehret V, Helbich TH, Grillari-Voglauer R, Jansen-Dürr P, Koš M, Polacek N, Grillari J, Schosserer M.
Heissenberger C, et al.
Nucleic Acids Res. 2019 Dec 16;47(22):11807-11825. doi: 10.1093/nar/gkz1043.
Nucleic Acids Res. 2019.
PMID: 31722427
Free PMC article.
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