Rare variants lowering the levels of coagulation factor X are protective against ischemic heart disease

Haematologica. 2020 Jul;105(7):e365-e369. doi: 10.3324/haematol.2019.237750. Epub 2019 Nov 7.

Elvezia Maria Paraboschi^{1

2}, Amit Vikram Khera^{3

4

5}, Piera Angelica Merlini⁶, Laura Gigante⁷, Flora Peyvandi^{8

9}, Mark Chaffin^{3

4

5}, Marzia Menegatti⁸, Fabiana Busti¹⁰, Domenico Girelli¹⁰, Nicola Martinelli¹⁰, Oliviero Olivieri¹⁰, Sekar Kathiresan^{3

4

5}, Diego Ardissino⁷, Rosanna Asselta^{1

2}, Stefano Duga^{1

2}

¹ Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.
² Humanitas Clinical and Research Center, Rozzano, Italy.
³ Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
⁴ Department of Medicine, Massachusetts General Hospital, Cardiology Division, Harvard Medical School, Boston, MA, USA.
⁵ Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.
⁶ Division of Cardiology, Azienda Ospedaliera Ospedale Niguarda Cà Granda, Milan, Italy.
⁷ Division of Cardiology, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
⁸ Angelo Bianchi Bonomi Haemophilia and Thrombosis Centre, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico and Luigi Villa Foundation, Milan, Italy.
⁹ Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.
¹⁰ Department of Medicine, Section of Internal Medicine, University of Verona, Verona, Italy.

No abstract available

Publication types