Homozygous variant p.Ser427Pro in PNPLA1 is a preventive factor from atopic dermatitis

J Dermatol Sci. 2020 Jan;97(1):86-88. doi: 10.1016/j.jdermsci.2019.12.006. Epub 2019 Dec 12.

Authors

Naoki Watanabe¹, Michihiro Kono², Mutsumi Suganuma¹, Kana Tanahashi¹, Masashi Akiyama³

Affiliations

¹ Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
² Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan. Electronic address: miro@med.nagoya-u.ac.jp.
³ Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan. Electronic address: makiyama@med.nagoya-u.ac.jp.

PMID: 31864761
DOI: 10.1016/j.jdermsci.2019.12.006

No abstract available

Publication types

Letter

MeSH terms

Case-Control Studies
Ceramides / biosynthesis*
Dermatitis, Atopic / genetics*
Dermatitis, Atopic / pathology
Disease Resistance / genetics*
Epidermis / pathology
Healthy Volunteers
Homozygote
Humans
Lipase / genetics*
Lipase / metabolism
Polymorphism, Single Nucleotide
Protective Factors

Substances

Ceramides
Lipase
PNPLA1 protein, human