Treatment Strategies for Tardive Dyskinesia

J Clin Psychiatry. 2019 Dec 24;81(1):NU18041BR4C. doi: 10.4088/JCP.NU18041BR4C.

Abstract

Tardive dyskinesia (TD), a condition of potentially irreversible abnormal involuntary movements that is associated with dopamine receptor blocking agents (DRBAs), produces significant impairment of functioning and quality of life for patients. Contrary to expectations, TD has not vanished despite the introduction of SGAs. Instead, changing prescription practices and increased off-label prescription of DRBAs have placed more patients than ever at risk of this potentially dangerous and disabling condition. This activity provides an overview of treatment strategies for TD as part of an individualized management plan, including DRBA medication adjustment and antidyskinetic treatment.

Publication types

  • Review

MeSH terms

  • Antipsychotic Agents / administration & dosage
  • Antipsychotic Agents / adverse effects
  • Dopamine Antagonists / administration & dosage
  • Dopamine Antagonists / adverse effects
  • Humans
  • Tardive Dyskinesia / drug therapy
  • Tardive Dyskinesia / therapy*

Substances

  • Antipsychotic Agents
  • Dopamine Antagonists