Unexpected High Levels of BRN2/POU3F2 Expression in Human Dermal Melanocytic Nevi

J Invest Dermatol. 2020 Jun;140(6):1299-1302.e4. doi: 10.1016/j.jid.2019.12.007. Epub 2019 Dec 24.

Authors

Arash Chitsazan¹, Duncan Lambie², Blake Ferguson¹, Herlina Y Handoko¹, Brian Gabrielli³, Graeme J Walker⁴, Glen M Boyle¹

Affiliations

¹ QIMR Berghofer Medical Research Institute, Herston, Australia.
² IQ Pathology, West End, Brisbane, Australia and The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia.
³ Mater Medical Research Institute, The University of Queensland, Translational Research Institute, Brisbane, Australia.
⁴ QIMR Berghofer Medical Research Institute, Herston, Australia; Experimental Dermatology, The University of Queensland Diamantina Institute, Translational Research Institute, Woolloongabba, Australia. Electronic address: g.walker1@uq.edu.au.

PMID: 31881210
DOI: 10.1016/j.jid.2019.12.007

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Cohort Studies
Dermis / cytology
Dermis / pathology
Disease Progression
Disease-Free Survival
Epidermis / pathology
Gene Expression Regulation, Neoplastic
Homeodomain Proteins / analysis
Homeodomain Proteins / metabolism*
Humans
Immunohistochemistry
Keratinocytes / metabolism
Melanocytes / metabolism
Melanoma / genetics
Melanoma / mortality
Melanoma / pathology*
Nevus, Pigmented / genetics
Nevus, Pigmented / pathology*
POU Domain Factors / analysis
POU Domain Factors / metabolism*
SOXE Transcription Factors / metabolism
Skin Neoplasms / genetics
Skin Neoplasms / mortality
Skin Neoplasms / pathology*
Survival Analysis

Substances

Homeodomain Proteins
POU Domain Factors
SOX10 protein, human
SOXE Transcription Factors
transcription factor Brn-2