Osteoarthritis: Pathology, Diagnosis, and Treatment Options

Benjamin Abramoff; Franklin E Caldera

doi:10.1016/j.mcna.2019.10.007

Osteoarthritis: Pathology, Diagnosis, and Treatment Options

Med Clin North Am. 2020 Mar;104(2):293-311. doi: 10.1016/j.mcna.2019.10.007. Epub 2019 Dec 18.

Authors

Benjamin Abramoff¹, Franklin E Caldera²

Affiliations

¹ Department of PM&R, University of Pennsylvania, Penn Medicine Rittenhouse, 1800 Lombard Street, Philadelphia, PA 19146, USA.
² Department of PM&R, University of Pennsylvania, Penn Medicine Rittenhouse, 1800 Lombard Street, Philadelphia, PA 19146, USA. Electronic address: Franklin.caldera@uphs.upenn.edu.

PMID: 32035570
DOI: 10.1016/j.mcna.2019.10.007

Abstract

Osteoarthritis (OA) is a worldwide endemic and debilitating disease. Previously thought to simply be damaged from "wear and tear," OA is now understood to be a complex interaction of local and systemic factors. This article reviews the pathology, symptoms, diagnosis, and various conservative, surgical, and novel treatments of OA.

Keywords: Arthralgia; Arthritis; Degenerative joint disease; Osteoarthritis.

Publication types

Review

MeSH terms

Humans
Osteoarthritis* / diagnosis
Osteoarthritis* / physiopathology
Osteoarthritis* / therapy
Patient Care Management / methods*