Epicardial Ablation of Ventricular Tachycardia in Arrhythmogenic Right Ventricular Cardiomyopathy

Fabrizio R Assis; Harikrishna Tandri

doi:10.1016/j.ccep.2020.05.005

Epicardial Ablation of Ventricular Tachycardia in Arrhythmogenic Right Ventricular Cardiomyopathy

Card Electrophysiol Clin. 2020 Sep;12(3):329-343. doi: 10.1016/j.ccep.2020.05.005. Epub 2020 Jul 8.

Authors

Fabrizio R Assis¹, Harikrishna Tandri²

Affiliations

¹ ARVC Program, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: fassis1@jhmi.edu.
² ARVC Program, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

PMID: 32771187
DOI: 10.1016/j.ccep.2020.05.005

Abstract

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease characterized by progressive fibrofatty replacement of the myocardium, right ventricular enlargement, and malignant ventricular arrhythmias. Ventricular tachycardia (VT) may be seen in all stages of the disease and is associated with sudden cardiac death. In patients who failed anti-arrhythmic medical therapy, catheter ablation has become an attractive therapeutic option to reduce VT burden and implantable cardioverter-defibrillator interventions. In this article, the authors aim to address the overall concepts of epicardial catheter ablation in ARVC, focusing on substrate characterization and ablation strategies.

Keywords: Arrhythmogenic right ventricular dysplasia/cardiomyopathy; Catheter ablation; Epicardial ablation; Ventricular tachycardia; Ventricular tachycardia recurrence.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Arrhythmogenic Right Ventricular Dysplasia / complications*
Catheter Ablation*
Epicardial Mapping*
Humans
Pericardium* / diagnostic imaging
Pericardium* / surgery
Tachycardia, Ventricular* / diagnosis
Tachycardia, Ventricular* / etiology
Tachycardia, Ventricular* / surgery