Management of benign liver tumors

Semin Pediatr Surg. 2020 Aug;29(4):150941. doi: 10.1016/j.sempedsurg.2020.150941. Epub 2020 Jul 24.

Abstract

Benign liver tumors in children are far less frequent than their malignant counterparts. Recently, there have been advances of diagnostic procedures and novel treatments with improved classification as a result. While malignant pediatric liver tumors have been comprehensively addressed by multicenter international tumor trials, benign tumors have more usually relied upon individualised workup and treatment. Due to the rarity and heterogeneity of these different entities, large studies are lacking. In this article the authors highlight the spectrum of benign liver tumors with special focus on specific clinical features, pathology, and treatment.

Keywords: Adenoma; Focal nodular hyperplasia; Hamartoma; Hemangioma; Inflammatory myofibroblastic tumor; Liver cysts; Pediatric liver tumors.

Publication types

  • Review

MeSH terms

  • Adenoma / pathology
  • Adenoma / physiopathology
  • Adenoma / therapy*
  • Child
  • Focal Nodular Hyperplasia / pathology
  • Focal Nodular Hyperplasia / physiopathology
  • Focal Nodular Hyperplasia / therapy*
  • Hamartoma / pathology
  • Hamartoma / physiopathology
  • Hamartoma / therapy*
  • Hemangioma / pathology
  • Hemangioma / physiopathology
  • Hemangioma / therapy*
  • Humans
  • Liver Neoplasms / pathology
  • Liver Neoplasms / physiopathology
  • Liver Neoplasms / therapy*