Oncologic Emergencies: Traditional and Contemporary

Jenna Spring; Laveena Munshi

doi:10.1016/j.ccc.2020.08.004

Oncologic Emergencies: Traditional and Contemporary

Crit Care Clin. 2021 Jan;37(1):85-103. doi: 10.1016/j.ccc.2020.08.004. Epub 2020 Oct 29.

Authors

Jenna Spring¹, Laveena Munshi²

Affiliations

¹ Interdepartmental Division of Critical Care Medicine, Department of Medicine, University of Toronto, Sinai Health System and University Health Network, Toronto, Ontario, Canada; Interdepartmental Division of Critical Care Medicine, Department of Medicine, University of Toronto, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Room D108, Toronto, Ontario M4N 3M5, USA. Electronic address: https://twitter.com/jennaspring.
² Interdepartmental Division of Critical Care Medicine, Department of Medicine, University of Toronto, Sinai Health System and University Health Network, Toronto, Ontario, Canada; Mount Sinai Hospital, 600 University Avenue, Suite 18-206, Toronto, Ontario M5G 1X5, Canada. Electronic address: laveena.munshi@sinaihealth.ca.

PMID: 33190777
DOI: 10.1016/j.ccc.2020.08.004

Abstract

The recognition and management of oncologic emergencies are becoming increasingly relevant in the intensive care unit, particularly in the era of novel biologic therapies. Early recognition and multidisciplinary collaboration are essential to improving patient outcomes. This article discusses aspects of diagnosis and management for important malignancy-associated emergencies.

Keywords: Cytokine release syndrome; Hyperleukocytosis and leukostasis; Immune-related adverse events; Malignant pericardial effusion; Metastatic spinal cord compression; Superior vena cava syndrome; Syndrome of inappropriate antidiuretic hormone; Tumor lysis syndrome.

Publication types

Review

MeSH terms

Emergencies*
Humans
Neoplasms* / complications
Neoplasms* / therapy