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Low amounts of heavy water increase the phase separation propensity of a fragment of the androgen receptor activation domain.
Protein Sci. 2021 Jul;30(7):1427-1437. doi: 10.1002/pro.4110. Epub 2021 May 24.
Protein Sci. 2021.
PMID: 33978290
Free PMC article.
Targeting androgen receptor phase separation to overcome antiandrogen resistance.
Xie J, He H, Kong W, Li Z, Gao Z, Xie D, Sun L, Fan X, Jiang X, Zheng Q, Li G, Zhu J, Zhu G.
Xie J, et al.
Nat Chem Biol. 2022 Dec;18(12):1341-1350. doi: 10.1038/s41589-022-01151-y. Epub 2022 Oct 13.
Nat Chem Biol. 2022.
PMID: 36229685
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