Long-Term Treatment of Postmenopausal Osteoporosis

Endocrinol Metab (Seoul). 2021 Jun;36(3):544-552. doi: 10.3803/EnM.2021.301. Epub 2021 Jun 22.

Abstract

Osteoporosis is an incurable chronic condition, like heart disease, diabetes, or hypertension. A large gap currently exists in the primary prevention of fractures, and studies show that an estimated 80% to 90% of adults do not receive appropriate osteoporosis management even in the secondary prevention setting. Case finding strategies have been developed and effective pharmacological interventions are available. This publication addresses how best to use the pharmacological options available for postmenopausal osteoporosis to provide lifelong fracture protection in patients at high and very high risk of fracture. The benefit of osteoporosis therapies far outweighs the rare risks.

Keywords: Denosumab; Diphosphonates; Duration of therapy; Osteoporosis, postmenopausal.

MeSH terms

  • Bone Density Conservation Agents* / therapeutic use
  • Diphosphonates / therapeutic use
  • Female
  • Humans
  • Osteoporosis* / chemically induced
  • Osteoporosis, Postmenopausal* / chemically induced
  • Osteoporosis, Postmenopausal* / drug therapy

Substances

  • Bone Density Conservation Agents
  • Diphosphonates