Pediatric Myeloproliferative Neoplasms

Farah El-Sharkawy; Elizabeth Margolskee

doi:10.1016/j.cll.2021.04.010

Pediatric Myeloproliferative Neoplasms

Clin Lab Med. 2021 Sep;41(3):529-540. doi: 10.1016/j.cll.2021.04.010.

Authors

Farah El-Sharkawy¹, Elizabeth Margolskee²

Affiliations

¹ Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
² Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA. Electronic address: margolskee@chop.edu.

PMID: 34304780
DOI: 10.1016/j.cll.2021.04.010

Abstract

Myeloproliferative neoplasms can present early in life and may present a diagnostic challenge. Very few studies have focused on the diagnosis, prognosis, and therapy for pediatric myeloproliferative neoplasms. This article focuses on chronic myeloid leukemia, essential thrombocythemia, polycythemia vera, and primary myelofibrosis in children.

Keywords: Chronic myeloid leukemia; Essential thrombocythemia; Myeloproliferative neoplasms; Pediatrics; Polycythemia vera; Primary myelofibrosis.

Publication types

Review

MeSH terms

Child
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*
Myeloproliferative Disorders* / diagnosis
Polycythemia Vera*
Primary Myelofibrosis* / diagnosis
Thrombocythemia, Essential* / diagnosis