Impact of Dietary Factors on Brugada Syndrome and Long QT Syndrome

Nutrients. 2021 Jul 21;13(8):2482. doi: 10.3390/nu13082482.

Abstract

A healthy regime is fundamental for the prevention of cardiovascular diseases (CVD). In inherited channelopathies, such as Brugada syndrome (BrS) and Long QT syndrome (LQTS), unfortunately, sudden cardiac death could be the first sign for patients affected by these syndromes. Several known factors are used to stratify the risk of developing cardiac arrhythmias, although none are determinative. The risk factors can be affected by adjusting lifestyle habits, such as a particular diet, impacting the risk of arrhythmogenic events and mortality. To date, the importance of understanding the relationship between diet and inherited channelopathies has been underrated. Therefore, we describe herein the effects of dietary factors on the development of arrhythmia in patients affected by BrS and LQTS. Modifying the diet might not be enough to fully prevent arrhythmias, but it can help lower the risk.

Keywords: Brugada syndrome; ROS; diet; glucose; ingredients; ketone bodies; long QT syndrome; sudden cardiac death.

Publication types

  • Review

MeSH terms

  • Alcohol Drinking
  • Animals
  • Brugada Syndrome / complications
  • Brugada Syndrome / physiopathology*
  • Death, Sudden, Cardiac / etiology*
  • Death, Sudden, Cardiac / prevention & control
  • Diet*
  • Diet, Ketogenic / adverse effects
  • Eating
  • Electrocardiography
  • Fatty Acids, Omega-3 / administration & dosage
  • Food*
  • Humans
  • Ketosis / complications
  • Long QT Syndrome / complications
  • Long QT Syndrome / physiopathology*
  • Oxidative Stress
  • Vagus Nerve / physiopathology
  • Vitamin D Deficiency / complications
  • Water-Electrolyte Imbalance / complications
  • Water-Electrolyte Imbalance / physiopathology

Substances

  • Fatty Acids, Omega-3