How does hip osteoarthritis differ from knee osteoarthritis?

M Hall; M van der Esch; R S Hinman; G Peat; A de Zwart; J G Quicke; J Runhaar; J Knoop; M van der Leeden; M de Rooij; I Meulenbelt; T Vliet Vlieland; W F Lems; M A Holden; N E Foster; K L Bennell

doi:10.1016/j.joca.2021.09.010

How does hip osteoarthritis differ from knee osteoarthritis?

Osteoarthritis Cartilage. 2022 Jan;30(1):32-41. doi: 10.1016/j.joca.2021.09.010. Epub 2021 Sep 29.

Authors

M Hall¹, M van der Esch², R S Hinman¹, G Peat³, A de Zwart⁴, J G Quicke³, J Runhaar⁵, J Knoop⁶, M van der Leeden⁷, M de Rooij⁴, I Meulenbelt⁸, T Vliet Vlieland⁸, W F Lems⁷, M A Holden³, N E Foster⁹, K L Bennell¹⁰

Affiliations

¹ Centre for Health Exercise and Sports Medicine, Department of Physiotherapy, School of Health Sciences, The University of Melbourne, Australia.
² Reade, Center for Rehabilitation and Rheumatology, Amsterdam, the Netherlands; Center of Expertise Urban Vitality, University of Applied Sciences Amsterdam, the Netherlands.
³ Primary Care Centre Versus Arthritis, School of Medicine, Keele University, UK.
⁴ Reade, Center for Rehabilitation and Rheumatology, Amsterdam, the Netherlands.
⁵ Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.
⁶ Vrije Universiteit Amsterdam, the Netherlands.
⁷ Reade, Center for Rehabilitation and Rheumatology, Amsterdam, the Netherlands; Amsterdam UMC, Location VUmc, Department of Rheumatology, Amsterdam, the Netherlands.
⁸ Leiden UMC, Leiden, the Netherlands.
⁹ Primary Care Centre Versus Arthritis, School of Medicine, Keele University, UK; STARS Research and Education Alliance, Surgical Treatment and Rehabilitation Service (STARS), The University of Queensland and Metro North Hospital and Health Service, Queensland, Australia.
¹⁰ Centre for Health Exercise and Sports Medicine, Department of Physiotherapy, School of Health Sciences, The University of Melbourne, Australia. Electronic address: k.bennell@unimelb.edu.au.

PMID: 34600121
DOI: 10.1016/j.joca.2021.09.010

Abstract

Hip and knee osteoarthritis (OA) are leading causes of global disability. Most research to date has focused on the knee, with results often extrapolated to the hip, and this extends to treatment recommendations in clinical guidelines. Extrapolating results from research on knee OA may limit our understanding of disease characteristics specific to hip OA, thereby constraining development and implementation of effective treatments. This review highlights differences between hip and knee OA with respect to prevalence, prognosis, epigenetics, pathophysiology, anatomical and biomechanical factors, clinical presentation, pain and non-surgical treatment recommendations and management.

Keywords: Exercise; Hip osteoarthritis; Knee osteoarthritis; Non-surgical treatments.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't
Review

MeSH terms

Humans
Osteoarthritis, Hip* / diagnosis
Osteoarthritis, Hip* / physiopathology
Osteoarthritis, Hip* / therapy
Osteoarthritis, Knee* / diagnosis
Osteoarthritis, Knee* / physiopathology
Osteoarthritis, Knee* / therapy
Prognosis