Tubercular Bronchoesophageal Fistula in an Adolescent Girl

Indian J Pediatr. 2022 Nov;89(11):1107-1109. doi: 10.1007/s12098-022-04116-0. Epub 2022 Feb 28.

Abstract

Bronchoesophageal fistula is a rare complication of Mycobacterium tuberculosis in children. An adolescent girl who was diagnosed of tubercular mediastinal lymphadenopathy with associated bronchoesophageal fistula at presentation, is reported here. This 16-y-old girl presented with high-grade fever, cough, decreased appetite, weight loss for 3 mo, and breathlessness for 10 d. Chest radiograph revealed hilar lymphadenopathy with bilateral pleural effusion. GA GeneXpert was positive for mycobacterium and rifampicin sensitivity. Despite antitubercular therapy cough persisted and there was a history of dry cough with food intake, especially more on liquids. Bronchoscopy and CECT chest confirmed bronchoesophageal fistula in the right main bronchus just below the carina. Child continued on tube feeding and antitubercular therapy. After completion of intensive phase, child improved with resolution of clinical symptoms and scarring of tract on repeat bronchoscopy. It is concluded that in children with combination of mediastinal lymphadenopathy and persistent cough following intake of food needs careful evaluation for trachea/bronchoesophageal fistula.

Keywords: Acquired, bronchoesophageal fistula; Mediastinal lymphadenopathy; Tracheoesophageal fistula; Tuberculosis.

MeSH terms

  • Adolescent
  • Antitubercular Agents / therapeutic use
  • Bronchial Fistula* / diagnosis
  • Bronchial Fistula* / etiology
  • Bronchial Fistula* / therapy
  • Child
  • Cough / complications
  • Esophageal Fistula* / diagnosis
  • Esophageal Fistula* / etiology
  • Esophageal Fistula* / therapy
  • Female
  • Humans
  • Lymphadenopathy* / drug therapy
  • Rifampin / therapeutic use
  • Tuberculosis, Lymph Node* / complications
  • Tuberculosis, Lymph Node* / diagnosis
  • Tuberculosis, Lymph Node* / drug therapy

Substances

  • Antitubercular Agents
  • Rifampin