Management of Stromal Lesions

Jingjing Yu; Kari Kansal

doi:10.1016/j.suc.2022.07.002

Management of Stromal Lesions

Surg Clin North Am. 2022 Dec;102(6):1017-1030. doi: 10.1016/j.suc.2022.07.002.

Authors

Jingjing Yu¹, Kari Kansal²

Affiliations

¹ 333 City Boulevard West, Suite 700, Orange, CA 92868, USA.
² Department of Surgery, University of California, Irvine, Orange, CA, USA. Electronic address: kkansal@hs.uci.edu.

PMID: 36335922
DOI: 10.1016/j.suc.2022.07.002

Abstract

Breast stromal lesions include fibroadenomas, phyllodes tumors, pseudoangiomatous stromal hyperplasia, periductal stromal tumors, and lipomas. Most of these lesions are benign and can be managed with observation or surgical excision. Phyllodes tumors, however, are subcategorized into benign, borderline, and malignant. Benign phyllodes tumors may be removed without a margin of breast tissue while borderline and malignant phyllodes tumors need a wide excision with a greater than 1 cm margin. Because malignant phyllodes tumors have a poor prognosis, efforts should be made to discuss their treatment in a multidisciplinary setting and enrollment in a clinical trial should be considered.

Keywords: Fibroadenoma; Fibroepithelial lesions; PASH; Periductal stromal tumor; Phyllodes tumor.

Publication types

Review

MeSH terms

Breast Neoplasms* / surgery
Female
Fibroadenoma* / pathology
Humans
Margins of Excision
Phyllodes Tumor* / diagnosis
Phyllodes Tumor* / surgery