Very Early Onset Inflammatory Bowel Disease Caused by a Novel Dominant Negative Mutation of Caspase Recruitment Domain 11 (CARD11)

J Clin Immunol. 2023 Apr;43(3):528-531. doi: 10.1007/s10875-022-01387-2. Epub 2022 Nov 29.
No abstract available

Publication types

  • Letter

MeSH terms

  • Age of Onset
  • CARD Signaling Adaptor Proteins / genetics
  • Caspase Activation and Recruitment Domain*
  • Guanylate Cyclase / genetics
  • Humans
  • Inflammatory Bowel Diseases*
  • Mutation
  • NF-kappa B / metabolism
  • Signal Transduction

Substances

  • CARD Signaling Adaptor Proteins
  • CARD11 protein, human
  • Guanylate Cyclase
  • NF-kappa B