Primary mediastinal choriocarcinoma in an 18-year-old male with pulmonary and brain metastasis: A case report

Clin Respir J. 2023 Oct;17(10):1082-1087. doi: 10.1111/crj.13691. Epub 2023 Aug 23.

Abstract

Primary mediastinal choriocarcinoma, also known as non-pregnant choriocarcinoma, is a rare malignancy unrelated to pregnancy, with a higher incidence in males. And primary mediastinal choriocarcinoma is mostly associated with organ and lymph node metastasis, with rapid progression and poor prognosis. Here, we report an extremely rare case of the primary anterior mediastinal choriocarcinoma that occurred in an 18-year-old man with multiple metastases of the lung and brain.

Keywords: choriocarcinoma; chorionic gonadotropin; male; mediastinal; multiple metastases.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Brain Neoplasms* / complications
  • Brain Neoplasms* / diagnostic imaging
  • Choriocarcinoma* / pathology
  • Choriocarcinoma* / secondary
  • Female
  • Humans
  • Lung / pathology
  • Male
  • Mediastinal Neoplasms* / pathology
  • Pregnancy
  • Testicular Neoplasms* / complications

Supplementary concepts

  • Nonseminomatous germ cell tumor