Progression of squamous carcinoma in situ of the vulva to invasive carcinoma after systemic bleomycin therapy

Aust N Z J Obstet Gynaecol. 1984 Feb;24(1):55-8. doi: 10.1111/j.1479-828x.1984.tb03324.x.

Abstract

Progression of squamous carcinoma in situ of the vulva to invasive carcinoma, in the same area, after systemic Bleomycin therapy, is described. Such progression is an exception and not the rule in the natural history of this disease. Conservative therapy should be used, especially in young women.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Bleomycin / therapeutic use*
  • Carcinoma in Situ / drug therapy*
  • Carcinoma in Situ / pathology
  • Carcinoma, Squamous Cell / drug therapy*
  • Carcinoma, Squamous Cell / pathology
  • Combined Modality Therapy
  • Female
  • Humans
  • Neoplasm Invasiveness
  • Vulva / pathology
  • Vulvar Neoplasms / drug therapy*
  • Vulvar Neoplasms / pathology

Substances

  • Bleomycin