Cerebral oligodendrogliomas in children: an analysis of 15 cases

Childs Nerv Syst. 1996 Sep;12(9):527-9. doi: 10.1007/BF00261605.

Abstract

The cases of 15 children operated on for cerebral pure oligodendroglioma were studied. Two groups of children were distinguished. Group I children presented with epilepsy (7 cases); their tumor was histologically benign in all cases. These children are all alive after a median follow-up of 72 months: however, 2 of them presented with a local recurrence, which was operated on, and are actually disease-free. Group 2 children presented with intracranial hypertension (8 cases); the tumor was anaplastic in 7 cases. Despite postoperative radiotherapy and chemotherapy 6 children died; their median survival time was 17 months. The present series shows the existence of a clear correlation between clinical presentation, histological grading and survival in childhood cerebral oligodendrogliomas.

MeSH terms

  • Adolescent
  • Brain Neoplasms / diagnosis
  • Brain Neoplasms / mortality*
  • Brain Neoplasms / therapy
  • Child
  • Child, Preschool
  • Combined Modality Therapy
  • Female
  • Humans
  • Infant
  • Magnetic Resonance Imaging
  • Male
  • Neoplasm Recurrence, Local / diagnosis
  • Oligodendroglioma / diagnosis
  • Oligodendroglioma / mortality*
  • Oligodendroglioma / therapy
  • Survival Analysis
  • Tomography, X-Ray Computed
  • Treatment Outcome