Abstract
Medullary thyroid cancer is a tumor of the thyroid C cells that occurs in sporadic and hereditary clinical settings. Genetic testing of at-risk individuals is available and has been applied to patient management. Plasma calcitonin levels are a sensitive marker for the presence of disease. Surgery offers the best hope for cure and also is an effective modality for managing metastatic and recurrent disease.
MeSH terms
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Biomarkers, Tumor / blood
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Calcitonin / blood*
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Carcinoma, Medullary / blood
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Carcinoma, Medullary / genetics*
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Carcinoma, Medullary / pathology
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Carcinoma, Medullary / secondary
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Carcinoma, Medullary / surgery
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Follow-Up Studies
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Genetic Testing
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Heterozygote
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Humans
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Multiple Endocrine Neoplasia Type 2a / blood
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Multiple Endocrine Neoplasia Type 2a / genetics
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Multiple Endocrine Neoplasia Type 2a / surgery
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Neoplasm Recurrence, Local / surgery
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Risk Factors
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Thyroid Gland / pathology
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Thyroid Neoplasms / blood
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Thyroid Neoplasms / genetics*
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Thyroid Neoplasms / pathology
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Thyroid Neoplasms / surgery
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Thyroidectomy
Substances
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Biomarkers, Tumor
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Calcitonin