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SARS-CoV-2 productively infects human gut enterocytes.
Lamers MM, Beumer J, van der Vaart J, Knoops K, Puschhof J, Breugem TI, Ravelli RBG, Paul van Schayck J, Mykytyn AZ, Duimel HQ, van Donselaar E, Riesebosch S, Kuijpers HJH, Schipper D, van de Wetering WJ, de Graaf M, Koopmans M, Cuppen E, Peters PJ, Haagmans BL, Clevers H. Lamers MM, et al. Among authors: riesebosch s. Science. 2020 Jul 3;369(6499):50-54. doi: 10.1126/science.abc1669. Epub 2020 May 1. Science. 2020. PMID: 32358202 Free PMC article.
An organoid-derived bronchioalveolar model for SARS-CoV-2 infection of human alveolar type II-like cells.
Lamers MM, van der Vaart J, Knoops K, Riesebosch S, Breugem TI, Mykytyn AZ, Beumer J, Schipper D, Bezstarosti K, Koopman CD, Groen N, Ravelli RBG, Duimel HQ, Demmers JAA, Verjans GMGM, Koopmans MPG, Muraro MJ, Peters PJ, Clevers H, Haagmans BL. Lamers MM, et al. Among authors: riesebosch s. EMBO J. 2021 Mar 1;40(5):e105912. doi: 10.15252/embj.2020105912. Epub 2021 Jan 11. EMBO J. 2021. PMID: 33283287 Free PMC article.
A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses.
Beumer J, Geurts MH, Lamers MM, Puschhof J, Zhang J, van der Vaart J, Mykytyn AZ, Breugem TI, Riesebosch S, Schipper D, van den Doel PB, de Lau W, Pleguezuelos-Manzano C, Busslinger G, Haagmans BL, Clevers H. Beumer J, et al. Among authors: riesebosch s. Nat Commun. 2021 Sep 17;12(1):5498. doi: 10.1038/s41467-021-25729-7. Nat Commun. 2021. PMID: 34535662 Free PMC article.