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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1965 1
1968 3
1969 2
1970 5
1971 3
1972 2
1973 3
1974 2
1975 17
1976 8
1977 8
1978 10
1979 8
1980 6
1981 13
1982 18
1983 13
1984 20
1985 29
1986 23
1987 34
1988 32
1989 34
1990 35
1991 36
1992 42
1993 36
1994 72
1995 62
1996 78
1997 95
1998 124
1999 123
2000 138
2001 169
2002 141
2003 166
2004 190
2005 199
2006 249
2007 243
2008 277
2009 308
2010 285
2011 298
2012 302
2013 330
2014 325
2015 316
2016 331
2017 329
2018 329
2019 361
2020 334
2021 383
2022 337
2023 261
2024 86

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6,913 results

Results by year

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Page 1
Exome sequencing and analysis of 454,787 UK Biobank participants.
Backman JD, Li AH, Marcketta A, Sun D, Mbatchou J, Kessler MD, Benner C, Liu D, Locke AE, Balasubramanian S, Yadav A, Banerjee N, Gillies CE, Damask A, Liu S, Bai X, Hawes A, Maxwell E, Gurski L, Watanabe K, Kosmicki JA, Rajagopal V, Mighty J; Regeneron Genetics Center; DiscovEHR; Jones M, Mitnaul L, Stahl E, Coppola G, Jorgenson E, Habegger L, Salerno WJ, Shuldiner AR, Lotta LA, Overton JD, Cantor MN, Reid JG, Yancopoulos G, Kang HM, Marchini J, Baras A, Abecasis GR, Ferreira MAR. Backman JD, et al. Nature. 2021 Nov;599(7886):628-634. doi: 10.1038/s41586-021-04103-z. Epub 2021 Oct 18. Nature. 2021. PMID: 34662886 Free PMC article.
When these were tested for association with 3,994 health-related traits, we found 564 genes with trait associations at P 2.18 10(-11). Rare variant associations were enriched in loci from genome-wide association studies (GWAS), but most (91%) we …
When these were tested for association with 3,994 health-related traits, we found 564 genes with trait associations at P 2.18 …
The atopic march and atopic multimorbidity: Many trajectories, many pathways.
Paller AS, Spergel JM, Mina-Osorio P, Irvine AD. Paller AS, et al. J Allergy Clin Immunol. 2019 Jan;143(1):46-55. doi: 10.1016/j.jaci.2018.11.006. Epub 2018 Nov 17. J Allergy Clin Immunol. 2019. PMID: 30458183 Review.
The atopic march recognizes the increased occurrence of asthma, allergic rhinitis, or both after atopic dermatitis (AD) onset. ...Recent investigations implicate disease severity and persistence, age of onset, parental atopic history, filaggrin (FLG) mutations, poly …
The atopic march recognizes the increased occurrence of asthma, allergic rhinitis, or both after atopic dermatitis (AD) onset. ...Rec …
Mendelian randomization study shows a causal effect of asthma on epilepsy risk.
Tang P, Guo X, Chong L, Li R. Tang P, et al. Front Immunol. 2023 Feb 13;14:1071580. doi: 10.3389/fimmu.2023.1071580. eCollection 2023. Front Immunol. 2023. PMID: 36860869 Free PMC article.
METHODS: Independent genetic variants strongly (P<5E-08) associated with asthma were from a recent meta-analysis of genome-wide association studies on 408,442 participants. ...CONCLUSION: The present MR study suggests that asthma is associ …
METHODS: Independent genetic variants strongly (P<5E-08) associated with asthma were from a recent meta-analysis of …
Potential drug targets for asthma identified in the plasma and brain through Mendelian randomization analysis.
Wang Y, Wang J, Yan Z, Liu S, Xu W. Wang Y, et al. Front Immunol. 2023 Sep 21;14:1240517. doi: 10.3389/fimmu.2023.1240517. eCollection 2023. Front Immunol. 2023. PMID: 37809092 Free PMC article.
Specifically, in plasma, we found that an increase of one standard deviation in IL1R1 and ECM1 was associated with an increased risk of asthma, while an increase in ADAM19 was found to be protective. ...In the brain, per 10-fold increase in ECM1 (OR, 1.05; 95% CI, 1 …
Specifically, in plasma, we found that an increase of one standard deviation in IL1R1 and ECM1 was associated with an increased risk …
Exploring the genetic association of allergic diseases with cardiovascular diseases: a bidirectional Mendelian randomization study.
Wang S, Liu H, Yang P, Wang Z, Hu P, Ye P, Xia J, Chen S. Wang S, et al. Front Immunol. 2023 Jun 2;14:1175890. doi: 10.3389/fimmu.2023.1175890. eCollection 2023. Front Immunol. 2023. PMID: 37334359 Free PMC article.
Genetic variants associated with AD, asthma, and CVD were identified and used as instrumental variables to investigate the genetically causal association between them. ...However, after a Bonferroni correction, only the association between as …
Genetic variants associated with AD, asthma, and CVD were identified and used as instrumental variables to investigate …
Asthma.
Martinez FD, Vercelli D. Martinez FD, et al. Lancet. 2013 Oct 19;382(9901):1360-72. doi: 10.1016/S0140-6736(13)61536-6. Epub 2013 Sep 13. Lancet. 2013. PMID: 24041942 Review.
Although the disease can start at any age, the first symptoms occur during childhood in most cases. Asthma has a strong genetic component, and genome-wide association studies have identified variations in several genes that slightly increase the risk of disea …
Although the disease can start at any age, the first symptoms occur during childhood in most cases. Asthma has a strong genetic compo …
Decoding the genetic and epigenetic basis of asthma.
Stikker BS, Hendriks RW, Stadhouders R. Stikker BS, et al. Allergy. 2023 Apr;78(4):940-956. doi: 10.1111/all.15666. Epub 2023 Feb 15. Allergy. 2023. PMID: 36727912 Review.
Alongside environmental factors, asthma susceptibility is strongly influenced by genetics. Given its high prevalence and our incomplete understanding of the mechanisms underlying disease susceptibility, asthma is frequently studied in genome-wide association …
Alongside environmental factors, asthma susceptibility is strongly influenced by genetics. Given its high prevalence and our incomple …
Epidemiology of Asthma and Influence of Ethnicity.
Moraes TJ, Sears MR, Subbarao P. Moraes TJ, et al. Semin Respir Crit Care Med. 2018 Feb;39(1):3-11. doi: 10.1055/s-0037-1618568. Epub 2018 Feb 10. Semin Respir Crit Care Med. 2018. PMID: 29427980 Review.
Asthma is a heterogeneous disorder with a complex etiology. Prevalence rates for asthma have been increasing in many countries over the past few decades. While it is unclear why this increase is occurring, the variation reported in asthma preval …
Asthma is a heterogeneous disorder with a complex etiology. Prevalence rates for asthma have been increasing in many co …
Occupational asthma.
Mapp CE, Boschetto P, Maestrelli P, Fabbri LM. Mapp CE, et al. Am J Respir Crit Care Med. 2005 Aug 1;172(3):280-305. doi: 10.1164/rccm.200311-1575SO. Epub 2005 Apr 28. Am J Respir Crit Care Med. 2005. PMID: 15860754 Review.
Substantial epidemiologic and clinical evidence indicates that agents inhaled at work can induce asthma. In industrialized countries, occupational factors have been implicated in 9 to 15% of all cases of adult asthma. Work-related asthma includes (1) immunolo …
Substantial epidemiologic and clinical evidence indicates that agents inhaled at work can induce asthma. In industrialized countries, …
Role of genomics in asthma exacerbations.
Herrera-Luis E, Hernandez-Pacheco N, Vijverberg SJ, Flores C, Pino-Yanes M. Herrera-Luis E, et al. Curr Opin Pulm Med. 2019 Jan;25(1):101-112. doi: 10.1097/MCP.0000000000000533. Curr Opin Pulm Med. 2019. PMID: 30334825 Review.
Although few genome-wide association studies of asthma exacerbations have been conducted up to date, they have revealed promising associations but with small effect sizes. Additionally, the analysis of interactions between genetic and environmental factors ha …
Although few genome-wide association studies of asthma exacerbations have been conducted up to date, they have revealed promis …
6,913 results