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38156584,37958732,37764102,36425759,36244618,35177474,34560573,34015056,33020446,32985205,32745153,32657004,31877196,31324924,31077130,30799983,30374707,30281950,30257868,29963044,29772718,29749430,29602068,29510577,29427674,29312229,29224776,28628829,28604814,28453414,27865865,27455306,27343592,27169394,26780774,26700306,26474845,26232502,26141411,25842954,25734776,25462348,25240225,25128688,25122471,24999046,24660173,24522926,24294965,24116707,24078045,23776161,23691572,23596297,23035222,22706108,22558090,22532690,21994714,21983687,21983358,21972018,21849445,21270149,20610727,20201613,20033657,19807023,19785778,19724077,19560386,19389311,19365546,18684824,18272767,18221766,18003726,17650322,17633327,17170436,17123638,17098336,16840324,16511093,16358742,15781125,15749121,15479431,15455686,15086382,14675635,13069658,12941926,12427336,12235215,12048029,11773388,11371617,11152493,11020163,10993930,10954546,10769064,10733173,10725549,10725436,10073362,9882377,9696880,9472936,9171450,9138643,9027696,8890474,8650169,8372441,8266721,8248909,7927962,7831964,7769668,7747448,7726007,7682406,7356392,6584516,6315770,6315580,6311733,6310039,6309671,6300395,6281556,6275037,6275036,6170256,6161603,5173260,4343406,4343405,4045429,3586602,3035276,3035275,3035274,3035273,2991610,2984458,2983005,2960402,2888283,2840874,2822845,2803004,2554132,2480764,2430550,2241578,2069506,2002550,1829246,1546448,1298880,1086219,828047,806519,208973,203425,203260,189743,178048,175126,71140,70498,65167,37436415,36651749,36260063,34203773,33992803,33765134,33568687,32571912,32237038,31375015,31240969,31147943,30819806,30563103,30301229,30158437,30124195,29934850,29446492,29430463,28975882,28947147,28428612,26325270,26202250,25940088,25751266,25526309,25008931,24889230,24673683,24488096,23345522,23329491,23268114,22927815,21931792,21901096,21829356,21786633,21590764,21173782,21073901,21071055,20719953,20703935,19838298,19657092,19398648,19211768,19112490,19031452,18668236,18398511,18391063,17923850,17617623,17283185,17229697,17114476,17094655,16928759,16927285,16870262,16272340,16189015,16123129,15623576,15496420,15455687,15184649,15105546,14718625,12904397,12388681,12021869,11752168,11270598,11145885,11136755,11119592,10927869,10570179,10489335,10440063,10358181,10211965,9779620,9656445,9520445,9495531,9416507,9348317,9094996,9079767,9017154,9001171,8972571,8970949,8894380,8648710,8609491,8259647,8237112,8145755,7559950,7529336,7513922,7474114,6107030,3614092,3468353,2998003,2809214,2099911,1851533,1529542,1435772,1433507,1322958,304841,87489,82606,36541713,35965362,35256564,35093090,34989322,34897432,33429820,33382686,33315162,33026893,32977150,32833836,32783269,32127157,32058622,31935221,31761294,31388035,31200655,31078790,30590172,30508616,30204960,29722137,29690975,29241927,28990185,28934068,28917830,28422453,28045068,27898336,27638328,27636994,26791356,26729373,26710928,26076463,26044958,25899150,25847322,25382487,24906316,24864645,24839142,24838992,24504889,24456159,24367282,24307683,24147092,24098154,23922166,23727605,23625330,23526679,23266637,23138777,22719263,22639997,22633399,22614755,22532670,22314436,22258522,22147889,22002956,21948702,21864119,21777673,21777535,21691042,21635976,21344627,21210484,21162708,20964118,20949531,20734338,20706998,20635217,20544697,20213698,20103369,20101700,19878742,19838013,19803455,19640928,19553938,19543118,19530188,19308703,19262028,19239086,19086026,18837045,18831060,18767966,18627040,18547886,18493797,18467846,18411254,17655765,17290579,17287257,16966464,16933211,16826533,16819604,16719272,16380922,16246000,15843411,15821733,14872406,12730719,12455636,12416640,12397630,12198594,12116204,12002154,11919685,11746009,11450388,11423730,11273483,11055885,10869115,10780921,10748410,10526661,10478256,10422009,10398269,10028874,9894165,9727740,9715119,9695307,9482640,9476331,9415466,9381776,9311573,9219013,9217221,9147883,9128933,9028454,9027508,8957512,8933346,8789766,8740915,8705415,8689589,8689588,8650122,8620859,8532626,8500790,8475459,8423611,8423610,8368260,8368240,8350593,8322808,8322177,8123061,8110412,8076064,8052563,8031542,8004795,7975801,7939823,7917121,7888142,7867169,7811427,7811423,7810558,7726229,7726220,7625440,7625439,7468660,7468656,7463021,7379414,7337303,7188929,7077622,7067161,7050679,6937274,6866577,6830545,6748015,6705242,6095765,5173210,4076260,4017277,3993682,3981578,3788975,3786205,3770566,3740099,3711327,3681906,3568444,3425976,3367608,3157194,3057982,2817778,2759011,2739665,2732992,2658590,2591070,2338339,2301476,2282714,2260610,2240038,2240030,2225526,2096762,2012129,2012128,1956066,1867259,1741973,1642816,1590982,1295244,1112852,1025650,964992,872834,842347,704970,537023,517578,495649,490136,201044,193472,177235[uid]

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[Screening of antiviral activity of samples from chaga Inonotus obliquus and humic acid from brown coal on Vero cell culture against ectromelia virus (Poxviridae: Orthopoxvirus; ECTV)].

Teplyakova TV, Kabanov AS, Ovchinnikova AS, Odnoshevskyh DA, Petrovskaya IF, Nepomnyashchikh TS, Pyankov OV. Teplyakova TV, et al. Vopr Virusol. 2023 Sep 21;68(4):277-282. doi: 10.36233/0507-4088-174. Vopr Virusol. 2023. PMID: 38156584 Russian.

The Viral Protein Poly(A) Polymerase Catalytic Subunit Interacts with Guanylate-Binding Proteins 2 to Antagonize the Antiviral Ability of Targeting Ectromelia Virus.

Gao Z, He X, Chen G, Fang Y, Meng Z, Tian H, Zhang H, Jing Z. Gao Z, et al. Int J Mol Sci. 2023 Oct 30;24(21):15750. doi: 10.3390/ijms242115750. Int J Mol Sci. 2023. PMID: 37958732 Free PMC article.

Guanylate-Binding Protein 2 Exerts GTPase-Dependent Anti-Ectromelia Virus Effect.

Gao Z, Meng Z, He X, Chen G, Fang Y, Tian H, Zhang H, Jing Z. Gao Z, et al. Microorganisms. 2023 Sep 8;11(9):2258. doi: 10.3390/microorganisms11092258. Microorganisms. 2023. PMID: 37764102 Free PMC article.

The ectromelia virus virulence factor C15 facilitates early viral spread by inhibiting NK cell contact.

Peauroi EM, Carro SD, Pei L, Reynoso GV, Hickman HD, Eisenlohr LC. Peauroi EM, et al. iScience. 2022 Nov 4;25(12):105510. doi: 10.1016/j.isci.2022.105510. eCollection 2022 Dec 22. iScience. 2022. PMID: 36425759 Free PMC article.

Complete deletion of Ectromelia virus p28 impairs virus genome replication in a mouse strain, cell type, and multiplicity of infection-dependent manner.

Dong J, Paszkowski P, Kocincova D, Ingham RJ. Dong J, et al. Virus Res. 2023 Jan 2;323:198968. doi: 10.1016/j.virusres.2022.198968. Epub 2022 Oct 13. Virus Res. 2023. PMID: 36244618 Free PMC article.

Targeting ectromelia virus and TNF/NF-κB or STAT3 signaling for effective treatment of viral pneumonia.

Pandey P, Al Rumaih Z, Kels MJT, Ng E, Kc R, Chaudhri G, Karupiah G. Pandey P, et al. Proc Natl Acad Sci U S A. 2022 Feb 22;119(8):e2112725119. doi: 10.1073/pnas.2112725119. Proc Natl Acad Sci U S A. 2022. PMID: 35177474 Free PMC article.

The epidermal growth factor ortholog of ectromelia virus activates EGFR/ErbB1 and demonstrates mitogenic function in vitro.

Morgis RA, Haan K, Schrey JM, Zimmerman RM, Hersperger AR. Morgis RA, et al. Virology. 2021 Dec;564:1-12. doi: 10.1016/j.virol.2021.09.003. Epub 2021 Sep 16. Virology. 2021. PMID: 34560573 Free article.

Resistance to lethal ectromelia virus infection requires Type I interferon receptor in natural killer cells and monocytes but not in adaptive immune or parenchymal cells.

Melo-Silva CR, Alves-Peixoto P, Heath N, Tang L, Montoya B, Knudson CJ, Stotesbury C, Ferez M, Wong E, Sigal LJ. Melo-Silva CR, et al. PLoS Pathog. 2021 May 20;17(5):e1009593. doi: 10.1371/journal.ppat.1009593. eCollection 2021 May. PLoS Pathog. 2021. PMID: 34015056 Free PMC article.

First Insight into the Modulation of Noncanonical NF-κB Signaling Components by Poxviruses in Established Immune-Derived Cell Lines: An In Vitro Model of Ectromelia Virus Infection.

Struzik J, Szulc-Dąbrowska L, Mielcarska MB, Bossowska-Nowicka M, Koper M, Gieryńska M. Struzik J, et al. Pathogens. 2020 Oct 4;9(10):814. doi: 10.3390/pathogens9100814. Pathogens. 2020. PMID: 33020446 Free PMC article.

Szulc-Dąbrowska L, Wyżewski Z, Gregorczyk-Zboroch KP, Toka FN, Szczepanowska J, Struzik J, Nowak-Życzyńska Z, Gieryńska M, Niemiałtowski M. Szulc-Dąbrowska L, et al. Acta Virol. 2020;64(3):307-324. doi: 10.4149/av_2020_305. Acta Virol. 2020. PMID: 32985205

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