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35792517,31193054,30896119,30511008,30327238,29962342,29207948,28431605,26726737,24958596,22935103,22656320,21108848,19202337,16716367,16339796,16319024,12221169,11445641,10745135,10739557,2209233,736823,38397235,38041431,38040034,37948995,37839080,37311680,36998234,36972931,36076926,35699229,35427439,35074613,34346499,33902225,33256324,33167837,32518081,32357846,31623876,31101435,31093799,30828969,30054298,30041933,30014764,29310369,29300972,29299012,29254829,28612835,28072961,28041799,27666374,27616477,27376954,27343025,27164704,27130255,26965689,26805782,26227957,26123052,26081110,25678562,25239001,25201786,24260406,23291686,23052599,22447335,22226368,22048857,21871821,21362476,21060012,20674936,20609299,20454899,20310007,20007524,19574929,19228174,18373410,17334266,17133502,16957495,16874760,16333759,16023262,15945070,15895552,12902021,12755040,12451202,12135967,11993189,11599221,11240563,10210919,9619150,8799630,8534513,8296538,8239283,8085432,7936288,3969211,2514400,2112314,34216614,33392778,28542381,27581950,38568475,38547196,38512679,38478096,38467734,38462606,38447455,38438854,38397079,38374041,38278691,38224281,38180358,38145611,38141856,38101398,38091510,38072238,38054895,37950283,37949858,37949680,37898963,37886910,37847226,37843849,37772684,37759179,37667390,37626421,37598860,37566030,37563653,37541846,37525083,37517035,37470810,37461300,37440031,37440029,37431188,37368868,37352388,37340860,37266762,37212212,37196678,37166002,37161652,37149645,37107599,37079300,37014713,36960552,36925418,36879317,36878275,36869969,36864049,36848111,36828035,36823441,36809767,36799027,36707904,36692340,36675067,36674978,36641423,36638182,36624280,36621975,36585109,36541444,36517915,36516294,36510411,36499139,36476387,36476347,36470129,36430231,36414996,36409355,36380488,36361749,36359796,36353934,36331259,36230957,36227727,36220610,36171642,36155660,36103153,36053979,35997131,35986567,35979925,35925583,35877057,35867854,35867795,35867206,35864098,35806387,35788411,35784551,35749908,35746899,35742893,35741857,35741796,35687365,35666053,35652445,35594156,35585302,35584922,35563815,35537597,35526389,35526386,35513515,35511239,35499206,35492244,35452662,35414105,35390481,35349636,35343238,35331405,35311646,35304484,35264561,35263583,35254903,35231560,35225340,35163733,35152189,35149592,35139868,35136347,35098363,35093159,35078129,35063911,35026838,34927205,34882275,34873168,34837396,34793837,34791217,34788402,34759270,34719765,34716339,34711807,34695439,34560904,34559230,34546528,34515757,34486988,34396852,34312939,34310194,34309047,34298918,34291567,34273111,34233951,34227061,34224862,34224817,34137233,34135352,34134906,34130995,34112891,34104971,34060036,33991015,33964137,33955002,33953837,33934221,33891869,33872730,33857770,33851480,33851459,33846769,33831349,33824499,33793036,33792664,33757809,33757554,33729061,33723707,33677035,33606969,33597231,33507371,33466875,33433879,33433877,33427744,33395982,33385254,33340656,33340485,33337568,33315139,33296728,33287888,33247623,33238751,33236327,33231622,33228809,33196954,33168090,33125873,33112398,33077188,33069577,33060592,33019767,33016371,33000527,32998447,32887382,32868457,32800686,32770663,32723825,32717343,32698485,32696431,32621835,32616036,32600092,32580013,32552286,32534165,32524518,32483373,32470423,32445516,32445072,32375900,32372501,32371126,32359380,32344399,32335390,32331858,32310161,32307925,32307445,32306062,32281751,32278709,32268088,32221286,32178712,32160553,32075919,32050117,32042174,32028086,32000863,31914230,31914227,31914226,31901894,31875517,31814692,31813996,31810826,31805953,31784375,31784286,31783118,31779819,31766579,31758070,31754701,31746411,31707213,31704274,31689548,31686426,31676550,31668596,31631020,31619490,31619230,31605779,31605140,31594549,31593566,31591561,31585367,31456032,31434868,31413119,31394102,31388113,31385551,31371703,31345061,31332438,31323276,31319082,31303188,31293010,31272932,31220553,31209033,31171723,31080113,31048364,31029751,31001583,30997656,30981863,30946927,30927137,30856120,30834979,30820146,30810811,30685464,30668823,30664784,30642748,30642396,30611021,30558096,30556376,30514770,30488149,30429331,30389008,30357887,30324308,30281416,30273642,30266742,30255971,30249412,30249303,30225910,30224383,30190489,30176346,30127392,30103325,30097039,30075745,30064895,30061394,30055837,30036493,30029693,30021151,30017992,30016411,29991141,29961810,29934063,29916145,29905849,29891053,29878075,29800053,29761896,29759981[uid]

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A homozygous Y443C variant in the RNPC3 is associated with severe syndromic congenital hypopituitarism and diffuse brain atrophy.

Bezen D, Kutlu O, Mouilleron S, Rizzoti K, Dattani M, Guran T, Yeşil G. Bezen D, et al. Am J Med Genet A. 2022 Sep;188(9):2701-2706. doi: 10.1002/ajmg.a.62888. Epub 2022 Jul 6. Am J Med Genet A. 2022. PMID: 35792517

West Nile Virus infection in a renal transplant recipient resulting in polioencephalomylelitis, quadriplegia, and global brain atrophy.

Kadkhoda K, Embil JM, McKibbin LR, McEachern J, Drebot MA. Kadkhoda K, et al. IDCases. 2019 May 3;17:e00551. doi: 10.1016/j.idcr.2019.e00551. eCollection 2019. IDCases. 2019. PMID: 31193054 Free PMC article.

Forensic Analysis of 25 Cases of Diffuse Brain Atrophy after Trauma.

Wang YB, Wang LL, Zhong SL. Wang YB, et al. Fa Yi Xue Za Zhi. 2019 Feb;35(1):48-51. doi: 10.12116/j.issn.1004-5619.2019.01.009. Epub 2019 Feb 25. Fa Yi Xue Za Zhi. 2019. PMID: 30896119 Free article. Chinese, English.

Do 2-year changes in superior frontal gyrus and global brain atrophy affect cognition?

Valdés Hernández MDC, Reid S, Mikhael S, Pernet C; Alzheimer's Disease Neuroimaging Initiative. Valdés Hernández MDC, et al. Alzheimers Dement (Amst). 2018 Aug 30;10:706-716. doi: 10.1016/j.dadm.2018.07.010. eCollection 2018. Alzheimers Dement (Amst). 2018. PMID: 30511008 Free PMC article.

Seaver LH, DeRoos S, Andersen NJ, Betz B, Prokop J, Lannen N, Jordan R, Rajasekaran S. Seaver LH, et al. Pediatr Neurol. 2018 Dec;89:26-30. doi: 10.1016/j.pediatrneurol.2018.07.014. Epub 2018 Aug 4. Pediatr Neurol. 2018. PMID: 30327238

Association Between Atrophy of the Caudate Nuclei, Global Brain Atrophy, Cerebral Small Vessel Disease and Mild Parkinsonian Signs in Neurologically and Cognitively Healthy Subjects Aged 45-84 Years: A Crosssectional Study.

Camarda C, Torelli P, Pipia C, Battaglini I, Azzarello D, Rosano R, Ventimiglia GD, Sottile G, Cilluffo G, Camarda R. Camarda C, et al. Curr Alzheimer Res. 2018;15(11):1013-1026. doi: 10.2174/1567205015666180702111110. Curr Alzheimer Res. 2018. PMID: 29962342

Homozygous GRID2 missense mutation predicts a shift in the D-serine binding domain of GluD2 in a case with generalized brain atrophy and unusual clinical features.

Ali Z, Zulfiqar S, Klar J, Wikström J, Ullah F, Khan A, Abdullah U, Baig S, Dahl N. Ali Z, et al. BMC Med Genet. 2017 Dec 6;18(1):144. doi: 10.1186/s12881-017-0504-6. BMC Med Genet. 2017. PMID: 29207948 Free PMC article.

Global brain atrophy and metabolic dysfunction in LGI1 encephalitis: A prospective multimodal MRI study.

Szots M, Blaabjerg M, Orsi G, Iversen P, Kondziella D, Madsen CG, Garde E, Magnusson PO, Barsi P, Nagy F, Siebner HR, Illes Z. Szots M, et al. J Neurol Sci. 2017 May 15;376:159-165. doi: 10.1016/j.jns.2017.03.020. Epub 2017 Mar 16. J Neurol Sci. 2017. PMID: 28431605

Measuring Global Brain Atrophy with the Brain Volume/Cerebrospinal Fluid Index: Normative Values, Cut-Offs and Clinical Associations.

Orellana C, Ferreira D, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Lovestone S, Simmons A, Wahlund LO, Westman E; AddNeuronMed consortium and for the Alzheimer''s Disease Neuroimaging Initiative. Orellana C, et al. Neurodegener Dis. 2016;16(1-2):77-86. doi: 10.1159/000442443. Epub 2015 Dec 19. Neurodegener Dis. 2016. PMID: 26726737

Global brain atrophy but not hippocampal atrophy is related to type 2 diabetes.

Wisse LE, de Bresser J, Geerlings MI, Reijmer YD, Portegies ML, Brundel M, Kappelle LJ, van der Graaf Y, Biessels GJ; Utrecht Diabetic Encephalopathy Study Group; SMART-MR Study Group. Wisse LE, et al. J Neurol Sci. 2014 Sep 15;344(1-2):32-6. doi: 10.1016/j.jns.2014.06.008. Epub 2014 Jun 14. J Neurol Sci. 2014. PMID: 24958596

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